Some common symptoms of glomerular disease are:
- High blood pressure
- Decreasing frequency of urination
- Fluid retention
- Swelling in lower legs, face, feet and abdomen
- Blood loss in urine
Glomerular disease is a disorder of the kidneys, in which the normal functioning of the kidneys is disturbed and the chemical balance is not maintained in your blood and urine. Healthy kidneys flush out toxins and waste materials in the urine and retain red blood corpuscles and proteins in the blood itself. But in case of glomerular disease, toxins are retained in the blood, whereas red blood cells and proteins get filtered out in the urine. This disorder can be either acute – meaning sudden occurrence or it can be chronic – meaning it builds up over a period. To understand what glomerular disease is, it is important to understand the functioning of kidneys.
The kidneys are bean-shaped fist-sized structures located near the rib cage. They have tiny structures called nephrons, which are filtering units for blood. These nephrons are made up of glomeruli and tubules. The function of glomeruli is to filter wastes and excess fluids. The function of tubules is to convert wastes into urine. In glomerular disease, the filtration process of the blood gets affected.
The causes include:
The treatment of glomerular disease depends upon the severity of symptoms, the type of disease and the cause of the disease. Your specialist at Medanta that recommend may medications that comprise of:..
The treatment of glomerular disease depends upon the severity of symptoms, the type of disease and the cause of the disease. Your specialist at Medanta that recommend may medications that comprise of:
Immunosuppressant medications like steroids are used to treat glomerular disease. If the disease is found to be rapidly progressive, plasmapheresis is used to remove blood components responsible for inflammation.
Management of high blood pressure is important to decrease the damages onto the kidneys. Therefore, drugs are prescribed to decrease the amount of proteins in urine and to decrease the progression of glomerular disease.
If left untreated, glomerular disease could lead to complications such as high blood pressure, acute kidney failure, chronic kidney failure and nephrotic syndrome. Acute kidney failure is likely to occur with acute glomerulonephritis. If glomeruli are incapable of filtering out waste, toxins accumulate in blood. In such cases, hemodialysis may be required to remove toxins from blood externally. This could be suggested as a temporary measure until the kidneys are restored to their original functionality, or be a permanent one in case the damages to the kidney are too severe to be treated.
If the functionality of your kidneys is beyond restoration, your nephrologist may suggest a kidney transplantation procedure. In this, a healthy kidney from a donor is transplanted into you by surgical means.
If you have symptoms like lack of appetite, muscle cramps in the night, nausea, vomiting, fatigue, dry and itchy skin, etc. you are advised to immediately contact your doctor.
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