Gilbert’s Syndrome (GS) is an inherent disease of the liver. It is a harmless genetic condition in which the liver enzyme (the protein molecule) becomes abnormal and cannot properly process bilirubin (waste due to worn out-red blood cells). It is generally due to a reduced number of chemicals in the liver. People with this disease experience elevated levels of bilirubin pigment, which may lead to yellowing of eyes and skin. It is a genetic condition and is examined when you take a blood test and that reveals high bilirubin levels.
Symptoms of GS are not clearly identified in elevated levels of bilirubin. Most of the people don’t come to a realisation of having it, because the bilirubin levels mostly stay within normal limits and rarely rise – that too slightly, to an extent that is tolerable. However, substances that are glucuronidated by the affected enzymes could cause symptoms such as:
The only cause of Gilbert’s Syndrome is an abnormal gene from either parent. It affects the liver and gives birth to an excessive amount of bilirubin. A gene in the liver controls enzyme which breaks down the bilirubin. A person with an abnormal gene stores a large amount of bilirubin. The syndrome is caused by:
Gilbert’s Syndrome usually has no symptoms and can cause mild jaundice. Mild but prolonged jaundice can be a cause of worry as it increases the chances of serious liver disorders.
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Gilbert’s Syndrome usually has no symptoms and can cause mild jaundice. Mild but prolonged jaundice can be a cause of worry as it increases the chances of serious liver disorders.
At Medanta, the diagnostic plans for this disease include:
Gilbert’s Syndrome does not require major treatment, as it isn't a serious condition. Patients are known to have normal life expectancy and healthy lifestyles without treatment. In specific cases, however, jaundice can be managed by a balanced d..
Gilbert’s Syndrome does not require major treatment, as it isn't a serious condition. Patients are known to have normal life expectancy and healthy lifestyles without treatment. In specific cases, however, jaundice can be managed by a balanced diet and adequate intake of water. If the symptoms of jaundice get too unsettling, patients may benefit from Phenobarbital, a medicine to lower bilirubin levels.
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